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2013年9月26日星期四

Severe Anemia Linked to Higher Death Risk After Heart Surgery: MedlinePlus

Severe Anemia Linked to Higher Death Risk After Heart Surgery: MedlinePlus


 







Severe Anemia Linked to Higher Death Risk After Heart Surgery


Condition should be treated before elective procedures if possible, researcher says


By Robert Preidt

Thursday, October 4, 2012



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THURSDAY, Oct. 4 (HealthDay News) — Anemia is a risk factor for complications and death following heart surgery, and elective heart surgeries should be delayed to treat moderate to severe anemia, a new study suggests.
In the study, Italian researchers compared the outcomes of 401 adult heart surgery patients with severe anemia and 401 heart surgery patients without severe anemia. The patients with severe anemia were nearly twice as likely to die and had a greater risk of stroke, prolonged mechanical ventilation and longer stays in the intensive care unit following surgery.
Similar results were found in patients with moderate anemia, according to the study in the October issue of The Annals of Thoracic Surgery.
“Unlike other recognized risk factors for cardiac surgery patients, such as advanced age and poor kidney function, anemia can be corrected with iron supplementation and medications that stimulate red blood cell production,” lead author Dr. Marco Ranucci said in a news release from the Society of Thoracic Surgeons. “Unfortunately, to correct anemia we need two to three weeks before the operation, which may be too long for many patients to wait.”
In people with anemia, the blood does not carry sufficient oxygen to the rest of the body. Blood loss, iron-poor diet or insufficient iron absorption from food all can lead to iron-deficiency anemia. Older adults are at risk for this common, easily treated anemia, the researchers noted.
Under current risk models, anemia is not considered a risk factor for survival following heart surgery, according to the release.
“Until it can be clearly demonstrated that correcting anemia improves outcomes, I think that working to correct and preserve the natural hemoglobin in a patient’s blood prior to surgery is a viable and safe option,” Ranucci said.
The study presents a convincing case for adding severe anemia to current models used to calculate the risks faced by heart surgery patients, Jeremiah Brown, an assistant professor at the Dartmouth Institute for Health Policy and Clinical Practice at the Geisel School of Medicine in Hanover, N.H., wrote in an accompanying journal commentary.
While the study found an association between severe anemia and post-heart surgery death risk, it did not prove a cause-and-effect relationship.



SOURCE: Society of Thoracic Surgeons, news release, Oct. 1, 2012


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2013年9月24日星期二

Press Announcements > FDA: Over-the-counter asthma inhalers containing chloroflouorocarbons (CFCs) will no longer be made or sold after Dec. 31, 2011


The U.S. Food and Drug Administration says users of epinephrine inhalers containing chlorofluorocarbons (CFCs) should plan now to get a prescription for a replacement product because these inhalers will not be made or sold after Dec. 31, 2011.
Epinephrine inhalers, marketed by Armstrong Pharmaceutical Inc. as Primatene Mist, are the only FDA-approved inhalers for the temporary relief of occasional symptoms of mild asthma that are sold over-the-counter in retail stores without a prescription. The product uses CFCs to propel the medicine out of the inhaler so that consumers can breathe it into their lungs.
However, Primatene Mist will no longer be available by year’s end because no CFC-containing epinephrine inhalers can be made or sold after Dec. 31, 2011, to comply with obligations made under the Montreal Protocol on Substances that Deplete the Ozone Layer. This is an international agreement signed by the United States, in which countries agreed to phase-out substances that deplete the ozone layer, including CFCs, after certain dates.


For more information please visit: CFCsL:
Press Announcements > FDA: Over-the-counter asthma inhalers containing chloroflouorocarbons (CFCs) will no longer be made or sold after Dec. 31, 2011