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2013年9月20日星期五

National Guideline Clearinghouse | Best evidence statement (BESt). The use of a warm vs. room temperature irrigation among pediatric patients undergoing urologic endoscopy.

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National Guideline Clearinghouse | Best evidence statement (BESt). The use of a warm vs. room temperature irrigation among pediatric patients undergoing urologic endoscopy.



Guideline Title


Best evidence statement (BESt). The use of a warm vs. room temperature irrigation among pediatric patients undergoing urologic endoscopy.

 

 



Bibliographic Source(s)





Cincinnati Children’s Hospital Medical Center. Best evidence statement (BESt). The use of a warm vs. room temperature irrigation among pediatric patients undergoing urologic endoscopy. Cincinnati (OH): Cincinnati Children’s Hospital Medical Center; 2012 May 8. 6 p. [17 references]




 

 


Guideline Status


This is the current release of the guideline.



2013年9月13日星期五

NIH statement on Food Allergy Awareness Week 2011—May 8–14, May 2, 2011 News Release - National Institutes of Health (NIH)

For Immediate Release
Monday, May 2, 2011 Contact:
NIAID Office of Communications
National Institute of Allergy and Infectious Diseases Home Page
301-402-1663



NIH statement on Food Allergy Awareness Week 2011—May 8–14
Daniel Rotrosen, M.D., and Anthony S. Fauci, M.D.
National Institute of Allergy and Infectious Diseases
National Institutes of Health


We observe Food Allergy Awareness Week this year acknowledging those who live every day with the concern that their exposure to certain foods may have the potential to trigger a life-threatening allergic reaction. The Centers for Disease Control and Prevention estimates that food allergy affects 5 percent of children under the age of 5 and 4 percent of older children in the United States. Scientists believe that the percentage of adults with food allergy is similar to that observed in older children. Until we can better understand why food allergy develops in one person and not another, and find out how to prevent and possibly cure food allergy, research and education are two of the best tools to help people living with this disorder.


In this regard, we at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, were gratified to work with 34 professional organizations, patient advocacy groups and federal agencies to develop new national guidelines for the diagnosis and management of food allergy, published in December 2010. The Guidelines for the Diagnosis and Management of Food Allergy in the United States: Report of the NIAID-Sponsored Expert Panel [Food Allergy Clinical Practice Guidelines] reflect long-awaited agreement across medical specialties about what food allergy is and how to diagnose and treat it. This summer, NIAID will publish a summary of the key points for patients.


The most common food allergens affecting Americans are milk, egg, peanut, tree nuts, soy, wheat, fish and crustacean shellfish. Currently, there is no way to prevent or cure food allergy. Food-allergic people must avoid certain foods and constantly guard against accidental exposures to hidden food allergens. Available medications can treat symptoms — which range from itching to a life-threatening drop in blood pressure — but only after the allergic reaction to food occurs.


Food Allergy Awareness Week was established in 1997 by the Food Allergy and Anaphylaxis Network (FAAN), a patient and family advocacy and education organization. This year, the Food Allergy Initiative, another advocacy group, joins FAAN in recognizing the commemorative week. Both FAAN and FAI participated in the development of the food allergy guidelines.


As the lead NIH institute for food allergy research, NIAID supports basic research and clinical studies to better understand the causes of food allergy and develop new preventions and treatments. Many of these efforts focus on how the immune systems of people with food allergy might be modified to eliminate their allergic reactions to food. Other studies are examining food allergy-associated allergic diseases, such as eosinophilic esophagitis, a condition that occurs when eosinophils (a type of immune cell associated with allergic reactions) accumulate in the esophagus, and are studying how genes, the environment and other allergic diseases may affect the development, persistence and severity of food allergy.


In 2010, NIAID renewed funding for two programs in food allergy research: the Consortium for Food Allergy Research (CoFAR) and Exploratory Investigations in Food Allergy. CoFAR conducts laboratory and clinical studies to test promising immune interventions to prevent and treat the condition and to determine the role of genetic and environmental factors in causing food allergy. Currently CoFAR is evaluating possible ways to treat people with food allergies, such as peanut allergy, by exposing them to the food allergen delivered as a liquid placed under the tongue, as a suppository or as part of a specialized skin patch. Exploratory Investigations in Food Allergy, which started in 2008 and is co-funded by FAAN and FAI, supports projects to improve understanding of food allergy. Approximately 29 grants have been awarded through this initiative, 90 percent of which fund investigators new to the field of food allergy research.


During Food Allergy Awareness Week, we recognize the people who live with food allergy, and we thank the patients and families who have given their time to participate in food allergy clinical trials. Their involvement in clinical research has contributed to the development of improved ways to prevent and treat this condition so that all people affected by food allergy can enjoy a better quality of life.


For more information about food allergy, visit NIAID’s Food Allergy Web portal: Food Allergy.


Dr. Fauci is Director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health in Bethesda, Maryland. Dr. Daniel Rotrosen is Director of the Division of Allergy, Immunology and Transplantation at NIAID.


Media inquiries can be directed to the NIAID Office of Communications at 301-402-1663, niaidnews@niaid.nih.gov.


NIAID conducts and supports research — at NIH, throughout the United States, and worldwide — to study the causes of infectious and immune-mediated diseases, and to develop better means of preventing, diagnosing and treating these illnesses. News releases, fact sheets and other NIAID-related materials are available on the NIAID Web site at http://www.niaid.nih.gov.


About the National Institutes of Health (NIH): NIH, the nation’s medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit www.nih.gov.


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NIH statement on Food Allergy Awareness Week 2011—May 8–14, May 2, 2011 News Release – National Institutes of Health (NIH)


Food Allergy Clinical Practice Guidelines:
Food Allergy Clinical Practice Guidelines


2013年9月11日星期三

NIH statement on World Asthma Day 2012 - May 1, 2012, April 30, 2012 News Release - National Institutes of Health (NIH)




DHHS, NIH News









For Immediate Release

Monday, April 30, 2012




NIH statement on World Asthma Day 2012 – May 1, 2012


Anthony S. Fauci, M.D., Director, National Institute of Allergy and Infectious Diseases,
Susan B. Shurin, M.D., Acting Director, National Heart, Lung, and Blood Institute,
Linda S. Birnbaum, Ph.D., Director, National Institute of Environmental Health Sciences,
Alan E. Guttmacher, M.D., Director, Eunice Kennedy Shriver National Institute of Child Health and Human Development


On World Asthma Day 2012, we at the National Institutes of Health stand with the Global Initiative for Asthma to renew our dedication to improving the quality of life for the millions of people living with asthma.

Asthma affects more than 230 million people worldwide, including more than 25 million people in the United States. There is no way to prevent, or to cure, asthma. Existing treatments focus on preventing or controlling disease symptoms, such as wheezing, chest tightness, shortness of breath and coughing. Despite these efforts, each year more than half of children and one-third of adults with asthma in the United States miss school or work because of the disease, approximately 17 million people require medical attention because of an asthma episode, and more than 3,000 asthma-related deaths occur.


Four NIH institutes — the National Institute of Allergy and Infectious Diseases (NIAID); the National Heart, Lung, and Blood Institute (NHLBI); the National Institute of Environmental Health Sciences (NIEHS); and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) — support basic and clinical research to understand the causes of asthma and the factors that contribute to its progression. Although each institute has a different focus, we all work together to help develop effective prevention and treatment strategies for the disease.


In March 2012, NIH, together with the Merck Childhood Asthma Network Inc., and the Agency for Healthcare Research and Quality in the U.S. Department of Health and Human Services, published a report that for the first time promotes standardization across asthma clinical studies. Asthma Outcomes in Clinical Research: Report of the Asthma Outcomes Workshop establishes common measures and data-collection methods to enable researchers to compare their results more efficiently. This standardization promises to enhance asthma clinical research and lead to improvements in the quality of asthma care.


In August 2011, NIH held a workshop, The Early Life Origins of Asthma: Strategies for Primary Prevention. Asthma typically begins early in childhood, and the goal of the workshop was to identify specific factors that may predict a person’s risk of developing asthma during the first 1,000 days of life. Such factors include environmental exposures, genetics and events that occur in pregnancy and early infancy. Workshop attendees concluded that understanding the early risk factors for asthma may provide an opportunity to prevent asthma before it begins.


NIH remains committed to working with individuals, families and health care professionals to reduce the worldwide burden of asthma. We commend our investigators who continue to make significant progress in asthma research, and we thank the people who have participated in NIH-sponsored asthma clinical studies, as well as to the nongovernmental organizations that provide support for those affected by this disease. We all share the hope that further research will uncover the causes of asthma so that the disease can one day be effectively prevented.


NIAID supports studies of the immune system’s role in the development of asthma and evaluates new approaches to treat and prevent the disease. NHLBI funds a broad asthma research portfolio — including studies on risk factors, mechanisms that influence disease severity, and identifying novel therapies — and the National Asthma Education and Prevention Program, which translates research into clinical practice to improve asthma control and quality of life. NIEHS supports research to understand how exposures to environmental agents trigger asthma, and how we can better prevent, diagnose and treat such exposures. NICHD conducts and supports research on all stages of human development, including research directed to those early life stages when chronic diseases such as asthma might be prevented.


NIAID conducts and supports research — at NIH, throughout the United States, and worldwide — to study the causes of infectious and immune-mediated diseases, and to develop better means of preventing, diagnosing and treating these illnesses. News releases, fact sheets and other NIAID-related materials are available on the NIAID Web site at http://www.niaid.nih.gov/.


Part of the National Institutes of Health, the National Heart, Lung, and Blood Institute (NHLBI) plans, conducts, and supports research related to the causes, prevention, diagnosis, and treatment of heart, blood vessel, lung, and blood diseases; and sleep disorders. The Institute also administers national health education campaigns on women and heart disease, healthy weight for children, and other topics. NHLBI press releases and other materials are available online at http://www.nhlbi.nih.gov/.


The NIEHS supports research to understand the effects of the environment on human health and is part of NIH. For more information on environmental health topics, visit http://www.niehs.nih.gov/. Subscribe to one or more of the NIEHS news lists (http://www.niehs.nih.gov/news/releases/newslist/index.cfm) to stay current on NIEHS news, press releases, grant opportunities, training, events, and publications.


About the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD):

The NICHD sponsors research on development, before and after birth; maternal, child, and family health; reproductive biology and population issues; and medical rehabilitation. For more information, visit the Institute’s Web site at http://www.nichd.nih.gov/. NICHD support was provided through the Best Pharmaceuticals for Children Act program, which seeks to improve pediatric therapeutics through preclinical and clinical drug trials that lead to drug labeling changes.


About the National Institutes of Health (NIH): NIH, the nation’s medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov/.


NIH…Turning Discovery Into Health



NIH statement on World Asthma Day 2012 – May 1, 2012, April 30, 2012 News Release – National Institutes of Health (NIH)