2013年9月28日星期六

Understanding The Various Treatments For Asthma



The purpose of asthma treatment is to prevent symptoms and to effectively control long-term asthma attacks. Treatment starts with educating the patient or the patient’s parents if the patient is young, about the symptoms of asthma and those things that may trigger an asthma attack. Treatment may include oral medications, inhalers and avoidance of what triggers the asthma attacks. Triggers vary from patient to patient.




If you recognize what triggers your symptoms of asthma you can avoid those triggers or minimize your exposure to them which will then lessen or eliminate your asthma attacks. Many things trigger asthma including irritants, allergens, respiratory infections, exercise and weather. One irritant trigger is dust. If a person’s asthma is triggered by dust they should have someone else dust the house and be sure to take measures to minimize dust especially in the bedroom.




Treatments for asthma include long-term control medications, inhaled corticosteroids, and rescue inhalers. There are many things that determine what medications will be right for your asthma symptoms including the age of the patient, the particular triggers that cause the asthma and your history of prior treatment and the success you had using those treatments.




There are various medications used to treat asthma. Rescue or quick-relief inhalers are used to quickly open airways during an asthma attack. Rescue inhalers may include one of the following medications:




Short-acting beta agonists such as Albuterol, Levalbuterol or Pirbuterol.




Ipratropium, which is a bronchodilator.




Oral and intravenous corticosteroids, which decrease inflammation in the airway.




If allergens are determined to cause asthma you will be prescribed allergy medications. Inhaled corticosteroids are medications that take several days to weeks to reach the full benefit level but have long-term success with low risk of side effects and are safe for patients to use over long periods of time. Oral medications such as leukotriene modifiers are used to prevent asthma symptoms for up to 24 hours after they are taken. Theophylline is a daily pill that is used to help keep airways open and relax the muscles around the airways so breathing is easier. This was a commonly used medication years ago but not used as much nowadays.




If allergies are determined to be a trigger for asthma it is important to take measure to control allergic reactions. Immunotherapy or allergy shots have been used successfully to reduce the allergic reaction experienced by exposure to certain allergens. A person will be tested to discover what the allergens are and then be given an allergy shot schedule; usually once a week for a few months, and then once a month for a period of one to five years depending on how severe the allergy has been determined to be.




Allergy medications can be oral or nasal spray and are usually a combination of antihistamines and decongestants. Corticosteroid, Cromolyn and Ipratropium nasal sprays are commonly used to control allergy symptoms.




Your doctor will discuss various treatment plans with you and your input will be important when deciding what treatment plan is best for you. Your treatment plan may change during the year especially if you have seasonal allergies, have asthma that is triggered by cold weather or participate in sports only part of the year.




Treatment typically is a combination of avoidance, lifestyle changes, medications and patient education about asthma. The treatment plan should be in writing with a way to measure success. Your doctor will want to have follow-up appointments in order to access how well your asthma is being controlled and to adjust your treatment plan to be sure that your asthma is well controlled.




If you would like to know more about Asthma and it’s remedies then click on ASTHMA AND TREATMENT below.


Genetic Risks for Asthma May Persist Into Adulthood: MedlinePlus

Genetic Risks for Asthma May Persist Into Adulthood: MedlinePlus


 







Genetic Risks for Asthma May Persist Into Adulthood


Continued disease, quality-of-life issues remain more likely, study found


By Robert Preidt

Friday, June 28, 2013



HealthDay news image

FRIDAY, June 28 (HealthDay News) — People with more genetic risks for asthma are not only more likely to develop the disease in childhood, but also more likely to continue to have asthma into adulthood, according to a new study.
Previous studies have linked several genes to increased asthma risk, so the researchers wanted to investigate the cumulative effect of those genes.
For the study, they analyzed data from 880 people in New Zealand who have been followed since they were born in 1972 or 1973. Those with more genetic risks for asthma developed asthma earlier in life than those with fewer genetic risks. Among study participants who developed asthma in childhood, asthma that persisted into adulthood was more likely in those with more genetic risks.
These patients also had more allergic reactions associated with severe and persistent asthma and developed lung function problems. Their quality of life also suffered because they missed work and school more often and were admitted to hospital more often due to asthma.
The study appears June 28 in The Lancet Respiratory Medicine.
“We’ve been able to look at how newly discovered genetic risks relate to the life course of asthma at an unprecedented level of resolution,” Daniel Belsky, a postdoctoral fellow at the Duke Institute for Genome Sciences and Policy and the Center for the Study of Aging and Human Development, said in a university news release.
However, much more research is needed before it may be possible to use genetic risk scores for asthma in patients, he noted.
“It will be important to explore how these genetic risks play out in environments that differ in terms of air pollution or other important, modifiable factors,” Belsky said.
He added that the study could lead to a better understanding of the biology of asthma and help efforts to develop new ways to prevent and treat asthma, which affects 26 million people in the United States.



SOURCE: Duke University, news release, June 27, 2013


HealthDay



More Health News on:

Asthma

Asthma in Children

Genes and Gene Therapy


CDC Features - May is Asthma Awareness Month

CDC Features – May is Asthma Awareness Month


May is Asthma Awareness Month



Photo: Father and sonAsthma is one of the most common lifelong chronic diseases. There are almost 26 million Americans living with asthma. The disease affects the lungs, causing repeated episodes of wheezing, breathlessness, chest tightness, and coughing. Although asthma cannot be cured, it is possible to manage asthma successfully to reduce and prevent asthma attacks, also called episodes. Successful asthma management includes knowing the warning signs of an attack, avoiding things that may trigger an attack, and following the advice of your healthcare provider. Using what you know about managing your asthma can give you control over this chronic disease. When you control your asthma, you will breathe better, be as active as you would like, sleep well, stay out of the hospital, and be free from coughing and wheezing. To learn more about how you can control your asthma, visit CDC’s asthma site.
Photo: A woman with an asthma inhalerAsthma affects people of all ages and backgrounds. In most cases, we don’t know what causes asthma, and we don’t know how to cure it. Certain factors may make it more likely for one person to have asthma than another. If someone in your family has asthma, you are more likely to have it. Regular physical exams that include checking your lung function and checking for allergies can help your healthcare provider make the right diagnosis. With your healthcare provider’s help, you can make your own asthma management plan so that you know what to do based on your own symptoms. Use your asthma medicine as prescribed and be aware of common triggers in the environment known to bring on asthma symptoms, including smoke (including second-hand and third-hand cigarette smoke), household pets, dust mites, and pollen. Limit or avoid exposure to these and other triggers whenever possible. The important thing to remember is that you can control your asthma.
To learn about the burden of asthma in the 36 states and territories funded by CDC’s National Asthma Control Program, see our new Asthma State Profiles.


 

More Information



National Recreation and Park Association"s Certified Park and Recreation Professional Test - NRPA CPRP Exam Secrets Study Guide

National Recreation and Park Association’s Certified Park and Recreation Professional Test – NRPA CPRP Exam Secrets Study Guide



NRPA CPRP Exam Secrets Study Guide – Buy Online

- How to Ace the National Recreation and Park Association’s Certified Park and Recreation Professional Examination without weeks and months of endless studying.


If you’d like to get the NRPA CPRP exam score you deserve, to quit worrying about whether your NRPA CPRP exam score is “good enough,” and to beat the test taking game so you can progress in your career, then this might be the most important message you read this year.


Our comprehensive NRPA CPRP exam study guide is written by our NRPA CPRP exam experts, who painstakingly researched every topic and concept you need to know to ace your NRPA CPRP exam. Our original research into the Certified Park and Recreation Professional (CPRP) exam, offered by the National Recreation and Park Association (NRPA), reveals specific weaknesses that you can exploit to increase your NRPA CPRP exam score more than you’ve ever imagined.



For More Informaion Please Click Here


Best Wishes


What Are Sinkholes and Where Do They Occur?

What Are Sinkholes and Where Do They Occur?



What Are Sinkholes and Where Do They Occur?


If you heard recent news reports about a devastating sinkhole in Florida, you may be wondering how this type of event occurs. 

According to the U.S. Geological Survey (USGS), sinkholes are most common in karst terrain, or regions where the rock below the land surface is soluble. When water from rainfall moves down through the soil, the rock begins to dissolve, creating spaces and caverns underground. If the underground spaces get too big, a sudden collapse occurs.


A


bout 20% of the United States is susceptible to sinkhole events, but the most damage tends to occur in Florida, Texas, Alabama, Missouri, Kentucky, Tennessee, and Pennsylvania.

Detailed geologic mapping, which defines areas of soluble rock at the surface and subsurface, can help educate land planners and policy makers about sinkhole risk.


If you know that you live in an area underlain by soluble rock, check your property for holes in the ground or cracks in your structure’s foundation.

Learn more about the science of sinkholes from the U.S. Geological Survey.




Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma

Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma
Yvonne J. Huang, MD



Affiliations
Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, Calif
, Craig E. Nelson, PhD
AffiliationsMarine Science Institute, University of California, Santa Barbara, Calif
, Eoin L. Brodie, PhD
AffiliationsEarth Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, Calif
, Todd Z. DeSantis, MS
AffiliationsEarth Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, Calif
, Marshall S. Baek, BS
AffiliationsDepartment of Anesthesia and Perioperative Care, University of California, San Francisco, Calif
, Jane Liu, MS
AffiliationsDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, Calif
, Tanja Woyke, PhD
AffiliationsUS Department of Energy, Joint Genome Institute, Walnut Creek, Calif
, Martin Allgaier, PhD
AffiliationsDepartment of Anesthesia and Perioperative Care, University of California, San Francisco, Calif
, Jim Bristow, MD
AffiliationsUS Department of Energy, Joint Genome Institute, Walnut Creek, Calif
, Jeanine P. Wiener-Kronish, MD
AffiliationsDepartment of Anesthesia and Perioperative Care, University of California, San Francisco, Calif
, E. Rand Sutherland, MD, MPH
AffiliationsDivision of Pulmonary and Critical Care Medicine, Department of Medicine, National Jewish Health, Denver, Colo
, Tonya S. King, PhD
AffiliationsDivision of Biostatistics, Department of Public Health Sciences, Pennsylvania State University, Hershey, Pa
, Nikolina Icitovic, MAS
AffiliationsDivision of Biostatistics, Department of Public Health Sciences, Pennsylvania State University, Hershey, Pa
, Richard J. Martin, MD
AffiliationsDivision of Pulmonary and Critical Care Medicine, Department of Medicine, National Jewish Health, Denver, Colo
, William J. Calhoun, MD
AffiliationsDivision of Allergy, Pulmonary, Immunology, Critical Care and Sleep, Department of Internal Medicine, University of Texas Medical Branch at Galveston, Galveston, Tex
, Mario Castro, MD
AffiliationsDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University, St Louis, Mo
, Loren C. Denlinger, MD, PhD
AffiliationsDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin Schools of Medicine and Public Health, Madison, Wis
, Emily DiMango, MD
AffiliationsDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY
, Monica Kraft, MD
AffiliationsDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University, Durham, NC
, Stephen P. Peters, MD, PhD
AffiliationsSection on Pulmonary, Critical Care, Allergy and Immunological Diseases, Department of Internal Medicine, Wake Forest University Health Sciences, Winston-Salem, NC
, Stephen I. Wasserman, MD
AffiliationsAllergy and Immunology Section, Department of Medicine, University of California San Diego, San Diego, Calif
, Michael E. Wechsler, MD
AffiliationsDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Mass
, Homer A. Boushey, MD
AffiliationsDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, Calif
, Susan V. Lynch, PhD
AffiliationsDivision of Gastroenterology, Department of Medicine, University of California, San Francisco, CalifReprint requests: Susan V. Lynch, PhD, Colitis and Crohn’s Disease Center, Division of Gastroenterology, Department of Medicine, Box 0538, University of California, San Francisco, CA 94143.
, National Heart, Lung, and Blood Institute’s Asthma Clinical Research Network


Affiliations
Investigators of the Asthma Clinical Research Network are listed in Appendix E1 in this article’s Online Repository at www.jacionline.org.
Received 17 July 2010; received in revised form 8 October 2010; accepted 27 October 2010. published online 03 January 2011.


Background
Improvement in lung function after macrolide antibiotic therapy has been attributed to reduction in bronchial infection by specific bacteria. However, the airway might be populated by a more diverse microbiota, and clinical features of asthma might be associated with characteristics of the airway microbiota present.


Objective
We sought to determine whether relationships exist between the composition of the airway bacterial microbiota and clinical features of asthma using culture-independent tools capable of detecting the presence and relative abundance of most known bacteria.


Methods
In this pilot study bronchial epithelial brushings were collected from 65 adults with suboptimally controlled asthma participating in a multicenter study of the effects of clarithromycin on asthma control and 10 healthy control subjects. A combination of high-density 16S ribosomal RNA microarray and parallel clone library-sequencing analysis was used to profile the microbiota and examine relationships with clinical measurements.


Results
Compared with control subjects, 16S ribosomal RNA amplicon concentrations (a proxy for bacterial burden) and bacterial diversity were significantly higher among asthmatic patients. In multivariate analyses airway microbiota composition and diversity were significantly correlated with bronchial hyperresponsiveness. Specifically, the relative abundance of particular phylotypes, including members of the Comamonadaceae, Sphingomonadaceae, Oxalobacteraceae, and other bacterial families were highly correlated with the degree of bronchial hyperresponsiveness.


Conclusion: The composition of bronchial airway microbiota is associated with the degree of bronchial hyperresponsiveness among patients with suboptimally controlled asthma. These findings support the need for further functional studies to examine the potential contribution of members of the airway microbiota in asthma pathogenesis.


Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma


ASMA
Actualidad Ultimas noticias – JANOes y agencias –
El asma podría estar relacionada con bacterias de las vías respiratorias
JANO.es y agencias · 21 Febrero 2011 11:32


Científicos de la Universidad de California en San Francisco han observado que las vías aéreas bronquiales de los pacientes asmáticos están infectadas por una colección más compleja y rica de microbios.


El asma podría tener una relación con la composición del grupo de bacterias que viven en los bronquios, un hallazgo que podría sugerir un nuevo tratamiento para esta común enfermedad inflamatoria, según un estudio de la Universidad de California en San Francisco, publicado en el Journal of Allergy and Clinical Immunology.


Utilizando nuevos métodos de detección, los investigadores han descubierto que la diversidad de microbios que habitan en el tracto respiratorio es mucho más grande de lo que se sospechaba, por lo que crean una comunidad microbiana compleja e interconectada que parece estar asociada al asma, similar a la que se ha encontrado en las enfermedades inflamatorias del intestino, la vaginitis, la periodontitis y, posiblemente, incluso en la obesidad.


En contra de la creencia popular, los científicos también vieron que las vías aéreas no son necesariamente ambientes totalmente estériles, incluso en personas sanas. Las vías aéreas de los asmáticos están infectadas por una colección más compleja y rica de bacterias. Estos descubrimientos podrían mejorar la comprensión de la biología del asma y potencialmente, llevar a terapias nuevas y mejoradas.


Durante los tres años que ha durado este proyecto piloto, los científicos recogieron muestras del revestimiento de las vías aéreas de 65 adultos con asma leve a moderado y de 10 sujetos sanos.


Después, utilizando una herramienta capaz de identificar cerca de 8.500 grupos distintos de bacterias en un único ensayo, desarrollaron los perfiles de los organismos presentes en cada muestra para buscar relaciones entre la comunidad de bacterias y las características clínicas de los pacientes con asma.


Descubrieron que las muestras de vías aéreas bronquiales de pacientes asmáticos contenían más bacterias que las muestras de pacientes sanos. Asimismo, encontraron una mayor diversidad de bacterias en los pacientes asmáticos con las vías aéreas más sensibles (una característica del asma).


Según el coautor de este estudio Homer Boushey, profesor de Medicina en la División de Cuidados Médicos Pulmonares y Críticos de la UCSF, “la gente piensa que el asma está causado por la inhalación de alérgenos, pero este estudio muestra que podría ser más complicado que eso, el asma podría conllevar la colonización de las vías aéreas por parte de múltiples bacterias”.


En los últimos años, los científicos habían comenzado a estudiar las comunidades de microorganismos de especies distintas (microbioma), que se encuentran tanto en individuos sanos como enfermos, para entender mejor su papel en una variedad de enfermedades. Pero la investigación en microbioma dentro de la enfermedad respiratoria es un terreno relativamente inexplorado.


Para Yvonne J. Huang, investigadora principal de este estudio, “conocemos bastante poco sobre la diversidad, complejidad y funciones colectivas de las bacterias que viven en el tracto respiratorio y de cómo pueden contribuir al desarrollo de enfermedades como el asma”.


Journal of Allergy and Clinical Immunology 2011;127:372-381
Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma


Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology – Home


University of California, San Francisco
University of California, San Francisco | www.ucsf.edu.


Actualidad Ultimas noticias – JANOes y agencias – El asma podria estar relacionada con bacterias de las vias respiratorias – JANO.es – ELSEVIER


Now, It"s Your Turn: How You Can Take Medicine Safely

How You Can Take Medicine Safely | NIH MedlinePlus the Magazine



08/21/2013 04:59 PM EDT

NIH
Related MedlinePlus Page: Medication Errors



pill warning label

Woman Taking Pill

Your doctor has prescribed a medicine. The pharmacist has filled the prescription. Now it’s up to you to take the medicine safely. Here are some tips that can help:


  • Make a list of all the medicines you take, including over-the-counter products and dietary supplements. Show it to all of your healthcare providers including physical therapists and dentists. Keep one copy in your medicine cabinet and one in your wallet or pocketbook. The list should include the: name of each medicine, doctor who prescribed it, reason it was prescribed, amount you take, and time(s) you take it.

  • Read and save in one place all written information that comes with the medicine.

  • Take your medicine in the exact amount and at the time your doctor prescribes.

  • Call your doctor right away if you have any problems with your medicine or if you are worried that it might be doing more harm than good. Your doctor may be able to change your prescription to a different one that will work better for you.

  • Use a memory aid to take your medicines on time. Some people use mealtime or bedtime as a reminder to take their medicine. Other people use charts, calendars, and weekly pill boxes. Find a system that works for you.

  • Do not skip doses of medication or take half doses to save money. Talk with your doctor or pharmacist if you can’t afford the prescribed medicine. There may be less costly choices or special programs to help with the cost of certain drugs.

  • Avoid mixing alcohol and medicine. Some medicines may not work correctly or may make you sick if taken with alcohol.

  • Take your medicine until it’s finished or until your doctor says it’s okay to stop.

  • Don’t take medicines prescribed for another person or give yours to someone else.

  • Don’t take medicine in the dark. To avoid making a mistake, turn your light on before reaching for your pills.

  • Check the expiration dates on your medicine bottles. Your pharmacist can probably tell you how to safely get rid of medicine you no longer need or that is out of date. The pharmacist might be able to dispose of it for you.

  • Make sure you store all medicines and supplements out of sight and out of reach of children. And don’t take your medicines in front of young children. They might try to copy you.



Find Out More



To sign up for regular email alerts about new publications and other information from the NIA, go to www.nia.nih.gov/health.




  • MedlinePlus: www.medlineplus.gov. Type in “medicines” in the Search box. Also, click on “Drugs & Supplements” to search for specific medicines.

  • Visit www.nihseniorhealth.gov, a senior-friendly website from the NIA and the National Library of Medicine. This website has health and wellness information for older adults. Special features make it simple to use. For example, you can click on a button to have the text read out loud or to make the type larger.


  • Centers for Medicare and Medicaid Services
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    21244–1850
    1–800–633–4227 (1–800–MEDICARE/toll-free) www.medicare.gov


  • Food and Drug Administration
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    1–888–463–6332 (toll-free)
    www.fda.gov


  • Partnership for Prescription Assistance
    1–888–477–2669 (toll-free)
    www.pparx.org